UCSF research scientist and Sunset District resident Peter Walter, PhD, is working with a team on a weapon against COVID-19. Photo by Steve Babuljak, courtesy UCSF.
By Thomas K. Pendergast
As scientists around the world scramble to make a vaccine to fight COVID-19, a San Francisco team of about 60 people – co-led by a Sunset District resident – is working on a unique potential solution that is roughly analogous to a molecular prophylactic.
UCSF’s Peter Walter, PhD, is leading this effort with his collaborator, Dr. Aashish Manglik, to test and produce AeroNabs, a nasal spray or nebulizing inhaler that would act as a first line of defense against infection in the nose, throat and lungs, where the virus enters the body.
The spray is not an anti-viral vaccine, but instead uses nanobodies, tiny molecular proteins that “sheath” parts of the virus attempting to penetrate the cell, thus preventing replication.
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